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S-1/A
OREXIGEN THERAPEUTICS, INC. filed this Form S-1/A on 04/09/2007
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New Jersey, NJ 08542
Attention: President/Chief Executive Officer
     Unless and until Orexigen is notified in writing to the contrary, all notices, communications and documents intended for you and related to this Agreement, if not delivered by hand, shall be mailed to your last known address as shown on Orexigen’s books. Notices and communications shall be mailed by registered or certified mail, return receipt requested, postage prepaid. All notices related to this Agreement shall be deemed received upon delivery or, if mailed, within five (5) days after mailing in accordance with this Section 10.
     11. Prior Agreements.
          This Agreement supersedes all prior agreements between you and Orexigen relative to your services as a consultant to Orexigen. This Agreement contains the entire understanding of the parties. Further, it shall be amended only in writing agreed to by both parties and shall not be assignable by you or by operation of law.
     Please indicate your acceptance of the foregoing by signing in the space provided below and returning one original letter to my attention.
             
    Sincerely,    
 
           
    OREXIGEN THERAPEUTICS, INC.    
 
           
 
  By:        
 
     
 
John F. Crowley,
   
 
      President and Chief Executive Officer    
     
ACCEPTED AND AGREED to this
___day of February, 2004
   
 
   
 
Lee G. Dante, M.D.
   
 
   
 
Social Security Number